Cellular biology and cytology laboratory

The research activity is mainly focused on the study of the inflammatory microenvironment of blood cancers, with a special focus on the functional characterization of extracellular vesicles.

Research Projects:

  • Study of the inflammatory mechanisms that regulate the relationship between tumor cells and the immune/stroma microenvironment in blood cancers, with particular reference to the role of extracellular vesicles.
  • Functional characterization of subpopulations of extracellular vesicles of patients with myelo/lymphoproliferative syndromes.
  • Study of the role of senescence in the pathogenesis of blood cancers.

 

Teaching:

  • Teaching "Molecular basis of hematological disorders" in the integrated course "Normal and leukemic stem cells", Master’s Degree Course in Medical Biotechnology (from 2019 to present) - University of Bologna.
  • Teaching "Blood Diseases" Master’s Degree Course in Medical Biotechnology (from 2011 to 2018) - University of Bologna.
  • Teaching "Biology and Genetics" Channel C- Degree Course Medicine and Surgery (2014-2015) - University of Bologna.
  • Teaching "Platelet-related disorders" School of Specialization in Hematology (from 2009 to present) - University of Bologna.
  • Tutoring students for internship-Master’s Degree in Medical Biotechnology and Biology - University of Bologna.
  • Tutoring PhD students of the Doctorate in Biomedical and Neuromotor Sciences - University of Bologna.

 

Laboratory Equipment:

  • Hood
  • Centrifuges (2)
  • Optical microscope
  • Flow Cytometry Facility (Flow cytometer Cytoflex, Hoods (2), incubator)
  • Cytology Facility (optical microscopes 2)

Principal investigator

Team

Collaboration:

Sandra Guastadini, Laboratory technician

Laboratory location

Hematology Institute “L. e A. Seragnoli”, DIMES

IRCCS Azienda Ospedaliera Universitaria di Bologna