Projects financed by national funds
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RandoMMness: the heterogenous spatial distribution of Multiple Myeloma unveiled by liquid biopsy
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Innovative and sustainable processes for the development of Vitamin D nutraceutical from fish waste: extraction, formulation and clinical study for the evaluation of its bioavailability and clinical equivalence (VITADWASTE)
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An app to shed the light on the window of opportunity of the first 1000 days of life
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Integrating cutting-edge tools for targeted approach to patients with adrenocortical tumors (COOL-REACT)
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Multi-omics analysis for the characterization of patients with glycemic alterations due to glucocorticoid and mineralocorticoid excess
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Atrial fibrillation and frailty development in older patients. Do therapeutic options exert a protective effect? From physical function, mood and cognition to metabolic pathways and “inflammageing”. The CAFFE (Cardioversion of Atrial Fibrillation and Frailty in the Elderly) Study
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Virus associated cancers: Discerning the potential of RNA based nanoimmunotherapeutics in 3D microfluidic biomimetic mdodels
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Fine-tuning corticosteroid signaling as a novel therapeutic strategy for heart regeneration
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The cardiomyocyte-intrinsic role of the glucocorticoid receptor in cardiac aging
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Early Life Exposure to per- and polyfluoroalkyl substaNces (PFAS) and health risks - ELENA
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Photobiomodulation as a tool for the well-being of microenvironmental cues in muscle-tendon unit (PoWeR)
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Tackling Ponto-Cerebellar Hypoplasia 6 due to mitochondrial RARS2 defect in patients’ derived stem cells: from disease mechanism of tissue-specificity to novel experimental therapies
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Exploiting advanced MOdels to Target glucose deprivation resistance during anti-angiogenIC therapy in OvarianN cancer (EMOTICON)
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A Preclinical, Precision Medicine Approach Based on Retargeted Herpesviruses with Oncoimmunotherapeutic Potential (PreMeRetHOn)
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AppenDectomy Vs ANti TNF-a in inducing Clinical and EnDoscopic remission in left-sided Ulcerative Colitis, implication for anemia and iron metabolism – A Randomized Clinical Trial and preclinical evaluation of nutraceuticals.
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Attitudes towards End-of-Life ISsues in Italy: the ELISI project
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Computationally aided Opto-mechano-fluidic pLatform for Label-free intelligent tumor microEnvironment Cell sorTing (COLLECT)
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CO-taRgeting REspiratory Complex I and the epigenetic regulator TET2: a novel anticancer strategy (CORRECT)
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Unravelling the circadian control of receptor tyrosine kinases: signaling cross talk with non-kinase receptors and interfering microRNAs
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Perinuclear actin cap regulation by YAP1 and membrane receptors: implications for cancer understanding at molecular level and therapy responsiveness
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snoRNA retaining transcripts (snoRTs) as post-transcriptional determinants of breast cancer cells phenotype
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Interaction of genomic and dietary aspects in gastric cancer risk: the global StoP project
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Highlights on the fate of endogenous and exogenous glucocorticoids by liquid chromatography/mass spectrometry. Untangling the metabolic pathways to predict cardiovascular and immune outcomes
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New and Old Psychoactive drugs Abuse and Neuroenhancers use Investigation among Current University Students (NO PANIC)
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Legal, ethical and social challenges of the Forensic DNA Phenotyping in Italy (LetFor)
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Role of Ribosomal protein L8 gene amplification in ovarian cancer
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In vivo models to define cytotoxic and immuno-mediated neuronal damages
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Enhancement of therapeutic response to standard-of-care drugs employed against hepatocellular carcinoma by hitting metabolic dependencies
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Direct or indirect effects of protein synthesis inhibitor enzymes from edible plants and mushrooms on intestinal health and microbiota
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Supporting medication adherence by the Elderly: development of an action framework for different healthcare settings
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Cellular and molecular mechanisms of thyroid disruption and tumorigenesis by perfluoroalkyl substances
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Metabolic hits in the road to colon cancer
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GDF15 as a key player and a potential target to tackle ageing and age-associated diseases: an in silico, in vitro and ex vivo study
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An artificial intelligence approach for risk prediction in patients with sepsis caused by klebsiella pneumoniae multidrug resistant strains
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Appropriate management of Bacteremic Febrile Neutropenia in High-Risk Hematological Patients. Relationship between duration of antibiotic administration, outcome and resistance profile
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On the development of neoantigen vaccine for HCC cure: from genomics of Hepatitis B Virus (HBV) integration in liver cells to immunological host response toward neoepitopes as novel immunotherapeutic approaches
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Expanding the knowledge of PTEN-Associated Disease (E-PAD)
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ADVANCE - Accelerated Diagnosis and non-inVasive strategies for AN early prediCtion of malignant transformation in hEreditary cancer predisposition syndrome: from NF1-associated benign precursor lesion to Malignant Peripheral Nerve Sheath Tumor (MPNST)
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Artificial intelligence for genomics and personalized medicine in myelodysplastic syndromes (MDS)
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Streamming: the dynamics of multiple myeloma minimal residual disease in the peripheral blood stream
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Integrated molecular analysis of endometrial carcinoma: translation of biomarker profiles into the clinical practice
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Functional dissection and therapeutic targeting of novel oncogenic pathways in cancer of unknown primary
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Assessing the Efficacy of Mitochondrial Complex, Targeting in Combined Therapies for Ovarian Cancer - AMICO
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Revealing vulnerabilities in early hematopoietic stages to identify novel therapeutic targets in pediatric non-DS AMKL
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Role of the gut microbiome in the outcome of diffuse large B-cell lymphoma patients treated with CAR-T cell therapy
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METAMUSCLE. Alterations related to muscle atrophy in the metabolic microenvironment, Indicators of inflammation and cardiometabolic risk factors
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Validation of artificial intelligence models for the description of ovary masses by ultrasound (virtual biopsy)
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Identification of diagnostic markers and molecular targets in uterine sarcomas
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Utility of three-dimensional imaging to increase the precision of tumor resection in hepatic surgery
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New combinatorial strategies for cardiac regeneration based on the dedifferentiation and proliferation of endogenous cardiomyocytes
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Role of cellular senescence in type II alveolar cells and potential involvement in the pathogenesis of idiopathic pulmonary fibrosis
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Neutralizing HER3/NRG1 axis by a combination of therapeutic aptamers and monoclonal antibodies
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Role of CD44 in the mechanisms of resistance to treatment with immune checkpoint inhibitors (IQIs) of non-small cell lung cancer (NSCLC)
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Qualis pater, talis filius?: use of a fractionator for screening human stem microvesicles with immunomodulatory potential
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Identification of new prognostic biomarkers for osteosarcoma
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Endometrial cancer and lifestyle: analysis of epigenetic alterations
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Biological, neurophysiological and kinematic markers in peripheral neuropathy after allogeneic stem cell transplantation in pediatric patients
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Developing treatment strategy for RBCK1 defect in patients' derived stem cell models
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Modifications of the motor program in the use of static or mobile collaborative robotic systems in manual load handling activities and characterized by repeated movements of the upper limb and its impact on risk profiles
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PMP 5.0: Development of technical and organisational tools to support prevention interventions for the development of resilient networked ecosystems
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3D platform for high-content analysis of anticancer drugs from the macro to the micro level using multicellular spheroids
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IDENTITA - Integrated network of Nutrition Management for the observation and Elaboration of personalized Nutrition Pathways against malnutation
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Development of organic electrochemical transistor tests for real-time quantification of emerging and re-emerging orthopoxvirus neutralizing antibodies
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The good use of green and blue spaces for health and wellness promotion
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House of Emerging Technologies - CTE COBO
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Interaction of genomic and dietary aspects in gastric cancer risk: the global stop project
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Effects of genomic profile on thromboembolic risk in patients with locally advanced or metastatic non-small-cell lung cancer
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Novel molecular mechanisms in chronic intestinal pseudo-obstruction
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Development of a plasmonic nanobiosensor for the rapid diagnosis of Shiga toxin producing E. coli human infections at the point of care
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Occult hepatitis B virus infection and HBV reactivation after switching to long acting therapy in patients living with HIV-1
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Role of clinical, histopathological and molecular markers for the optimization of the endoscopic resection technique and follow-up in patients with type-1 gastric neuroendocrine tumors
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Personalized medicine in myeloid neoplasms: explainable artificial intelligence solutions for next generation classification and management of the patients