ORGAN TRANSPLANTATION FROM DCD AND THE MANAGEMENT OF MULTIPLE ORGANS FAILURE INCLUDING REGENERATIVE MEDICINE

DIMEC is pleased to sponsor the conference "DCD organ transplantation and the management of multiple organ failure, including regenerative medicine."

Agenda

DECEMBER 1, 2023

08.00 Introduction to the Meeting

• Prof. Matteo Ravaioli – Dr. Antonio Siniscalchi
• Prof. Giovanni Molari
• Dr. Chiara Gibertoni
• Dr. Alessandro Nanni Costa
• Prof. Marco Seri

LIVER AND KIDNEY SESSION

WHAT DID WE LEARN AND WHAT HAVE WE STILL TO LEARN ABOUT DCD LIVER TRANSPLANTATION?

Moderators: Prof. Luciano de Carlis and Prof. Matteo Ravaioli

09.00 Which data during NRP should contraindicate the use of DCD liver for transplantation?
Dr. Damiano Patrono
comment 5 min Dott. Duilio Pagano

09.20 Ex-vivo strategies for DCD liver grafts: shorter CIT, HOPE, normothermic perfusion or a combination of these? Available evidence and how to decide
Dr. Riccardo De Carlis
comment 5 min Prof. De Simone Paolo

09.40 Anesthesiologic management of donor and recipient in the DCD setting
Prof. Gianni Biancofiore
comment 5 min Dr. Andrea De Gasperi

10.00 Italian experience and evolution of the DCD
Dr. Silvia Trapani
comment 5 min Prof. Renato Romagnoli

10.20 Discussion
Moderator: Prof. Matteo Cescon

10.40 Evolution of liver DCD in Switzerland and in Europe
Prof. Philip Dutkowski

Coffee break e poster session 30 min

WHAT DID WE LEARN AND WHAT HAVE WE STILL TO LEARN ABOUT DCD KIDNEY TRANSPLANTATION?

Moderators: Prof. Giuseppe Grandaliano and Prof. Andrea Buscaroli

11.30 Which data during NRP should contraindicate the use of DCD kidney for transplantation?

Prof. Quirino Lai

comment 5 min Prof. Gabriele Donati

11.50 Kidney biopsy in DCD: when & why?

Dr. Alessandro Del Gobbo

comment 5 min Prof. Umberto Maggiore

12.10 Postoperative management of DCD recipients: potential complications & how to manage

Prof. Giorgia Comai

comment 5 min Dr. Rossana Caldara

12.30 Immunosuppression in complex cases and how to manage DCD recipients

Prof. Gaetano La Manna

12.50 Discussion

Moderator: Prof. Antonia D’Errico

13.10 Evolution of kidney DCD in Sweden and in Europe
Prof. Tomas Lorant

13.30 Lunch symposium
Moderator: Prof. Ugo Boggi

• Italian school for DCD
  Prof. Adriano Peris

• How to train transplant surgeon
  Prof. Jacopo Romagnoli

• Exploring the potential of HOPE: Machine Perfusion and DCDs - a Success Story from Bologna
  Prof. Matteo Ravaioli

LUNG AND HEART SESSION

WHAT DID WE LEARN AND WHAT HAVE WE STILL TO LEARN ABOUT DCD LUNG TRANSPLANTATION?

Moderators: Prof. Gaetano Gargiulo and Prof. Lorenzo Rosso

14.30 Logistic model and organization for DCD in Emilia-Romagna

Dr. Nicola Alvaro

14.45 Anesthesiologic management of the donor during DCD lung procurement

Prof. Vanni Agnoletti

comment 5 min Dr. Massimo Baiocchi

15.00 Anesthesiologic management of the recipient during lung transplantation from DCD
Dr. Valentina Roncarati
comment 5 min Dr. Andrea Castelli

15.15 Bologna and Italian results with DCD
Dr. Filippo Antonacci
comment 5 min Prof. Lorenzo Rosso

15.30 Surgical management of lung transplantation from DCD
Dr. Pietro Bertoglio
comment 5 min Dr. Stefania Camagni

15.45 Postoperative management of DCD recipients: potential complications & how to manage
Dr. Elena Salvaterra
comment 5 min Dr. Piero Candoli

16.00 Discussion
Moderators: Dr. Domanico Pinelli, Prof. Nazzareno Gallie

16.20 Future projects forlung tranpslantation from DCD
Prof. Niccolò Daddi

Coffee break e poster 30 min

HEART FROM DCD MANY QUESTIONS

Moderators: Prof. Davide Pacini and Dr. Massimo Cardillo

17.00 Experimental background to develop heart transplantation from DCD
Dr. Luca Botta

17.15 Clinical protocols and results from DCD Heart transplantation worldwide
Dr. Sofia Martin-Suarez

17.30 Protocol for DCD Heart transplantation in Italy
Prof. Massimo Boffini

17.45 DCD Heart procurement in hospitals without cardiac surgery program: feasible?
Dr. Andrea Nanni

18.00 Discussion and round table
Moderator: Prof. Luciano Potena
Discussants with all presenters and Dr. Cerchierini, Dr. Antonio Siniscalchi,
Dr. Giuseppe Tarantino, Dr. Gabriela Sangiorgi, Dr. Lorenzo Maroni

DECEMBER 2, 2023

MANAGEMENT OF MULTIPLE ORGANS FAILURE AND REGENERATIVE MEDICINE

DCD AND MULTIPLE ORGANS FAILURE
Moderators: Dr. Antonio Siniscalchi and Dr. Cristina Morelli

08.30 What do we know and what do we need to improve for A-NPR e TA-NPR?
Dr. Marinella Zanierato

08.45 Strategies to decrease warm ischemic time and improve NRP
Dr. Francesco Procaccio

09.00 Ultrasound during NRP
Dr. Amedeo Bianchini

09.15 Pitfalls & troubleshooting during NRP
Dr. Marta Velia Antonini

09.30 ECLS and complex recipients
Dr. Cristiana Laici

09.45 DCD: Different risk of infections?
Prof. Maddalena Giannella

10.00 Infections, TDM and DCD recipient
Dr. Milo Gatti

10.15 Discussion and round table
Moderator: Dr. Andrea De Gasperi
Discussants with all presenters and Dr. Massimo Del Gaudio, Dr. Matteo Serenari,
Dr. Andrea Laurenzi, Dr. Chiara Zanfi, Dr. Federica Odaldi, Dr. Elisabetta Pierucci, Dr. Erika Cordella

11.00 Coffee break

REGENERATIVE MEDICINE

Moderators: Prof. Matteo Ravaioli and Prof. Fabio Piscaglia

11.30 DCD donation at the intersection between transplant and regenerative medicine
Prof. Giuseppe Orlando (video call)

EXTRACELLULAR VESICLES AND CLINICAL PERSPECTIVE
Moderators: Prof. Massimiliano Bonafe – Prof. Gianandrea Pasquinelli

12.00 Mesenchymal stem cells, extracellular vesicles, and organoids: pro & con during ex-vivo treatment for transplantation
Prof. Stefania Bruno

12.15 How to manage clinical studies involving cell therapy during ex-vivo perfusion
Prof. Teresa Rampino

12.30 Clinical applications of regenerative medicine during organ failure
Prof. Gabriele Matteo D’Uva

12.45 Extracellular vesicles in regenerative medicine
Prof. Lorenza Lazzari

13.00 Discussion and round table
Moderator: Prof. Francesca Bonifazi
Discussants with all presenters and Dr. Francesco Vasuri, Dr. Maurizio Baldassarre,
Dr. Giuliana Germinario

Conclusions meeting
Prof. Matteo Ravaioli – Dr. Antonio Siniscalchi

Registration for the course is free of charge, it can be done exclusively through online procedure on
our website:  www.mitcongressi.it by selecting the course from the catalog. It will not be guaranteed the
possibility to register at the congress venue.

A prize of €1,000 for first place and a prize of €500 for second place will be awarded at the congress to the two best posters to be presented during the dedicated session.
To apply, send an e-mail to the following address: alessandra.sulmicelli@mitcongressi.it