Research areas:
- Molecular bases for the penetration of the herpes simplex virus into the cell
- Innate cellular response during the entry of the herpes simplex virus (HSV)
- Preclinical engineering and effectiveness of oncolytic HSV directed towards specific tumor receptors, as a single therapy or in combination with CPI
- Immunological characterization of murine tumor samples treated with oncolytic viruses.
Teaching activity:
Internship for the preparation of the experimental degree thesis for the undergraduate course in Molecular and Industrial Biotechnology
Instrumentation available:
- Biosafety level 2 room for cell cultures, with a laminar flow booth, benchtop centrifuges, ultracentrifuge L-60 (Beckman), and CO2 incubators
- Freezers at -80°C and containers of liquid nitrogen for cell culture storage
- Molecular biology rooms with thermal cyclers, equipment for DNA electrophoresis, and microcentrifuges
- Equipment for protein electrophoresis and Western blot (Bio-Rad Protein and Trans-Blot system)
- Molecular imager ChemiDoc XRS+ with Image Lab Software (Bio-Rad)
- Inverted fluorescent microscope (Nikon)
- Direct motorized fluorescent microscope Eclipse Ni-E (Nikon)
- Glomax Discover with injectors for reading plates (Promega)
- Step One Plus – Real-Time PCR System (Applied Biosystem)
- C6 Flow Cytometer (BD Accuri)