Research projects
- The isolation and immuno-functional characterization of stem cells; the study of their differentiating capacity.
-The immuno-modulating and tolerogenic activity of stem cells.
- The study of the relation of human stem cells' lipid membrane profile and their biological properties of proliferation and differentiation.
- The selection of isolated stem cells (without considering subpopulation) from extra-embryonic and adult tissues for applications in regenerative medicine.
- The development of innovative selection methods to be applied to the stem-cell population, based on field flow fractionation.
- The development of methods for the analysis of biophysical parameters using 3D models of stem cell spheroids.
Ongoing research objectives
- The generation and characterization of 3D culture models for tissue-engineering approaches.
- The study of the differentiating capacity along the pancreatic-endocrine line of amniotic-membrane stem cells.
Databank of human stem cells
The activities of the research group have resulted in the creation of a biological databank for the cryoconservation of human stem cells. The samples will be used for research and in collaborations with clinical laboratories for the study of various pathologies.
The databank has mesenchymal cells isolated from the following: amniotic mebrane, chorionic membrane, umbilical cord, bone marrow, dental pulp, adipose tissue, intestinal mucosa, and pancreatic tissue; as well as epithelial cells isolated from the amniotic membrane.