Ginecologia e Fisiopatologia della Riproduzione Umana

Responsabile scientifico/Coordinatore - Prof.ssa Maria Cristina Meriggiola

Attività scientifica

  • La gestione ginecologica dei disturbi della differenziazione sessuale
  • Diagnosi e trattamento delle alterazioni endocrinologiche ginecologiche dall’età adolescenziale alla menopausa
  • La contraccezione femminile e maschile
  • L’ottimizzazione della terapia medica e chirurgica nei soggetti con disforia di genere
  • Ottimizzazione dell’approccio ormonale sostitutivo nelle donne con insufficienza ovarica precoce
  • Terapie ormonali e non in menopausa
  • Trattamento conservativo delle disfunzioni del pavimento pelvico (prolasso degli organi pelvici ed incontinenza urinaria)
  • Trattamento con chirurgico delle disfunzioni del pavimento pelvico (prolasso degli organi pelvici ed incontinenza urinaria)

Membri del gruppo

Stefania Alvisi

Assegnista di ricerca

Maurizio Baldassarre

Cat. D - area tecnica, tecnico - scientifica ed elaborazione dati

Claudio Foschi

Ricercatore a tempo determinato tipo b) (senior)

Maria Cristina Meriggiola

Professoressa associata

Altri membri

Dott.ssa Ilaria Mancini

Dott.ssa Isabella Orsili

Dott.ssa Giulia Giacomelli

Silvia Cerpolini

Collaborazioni nazionali

  • Il gruppo collabora con le seguenti figure interne al Policlinico S. Orsola-Malpighi: Prof. Morselli e Dott.ssa Pinto (Chirurgia Plastica), Prof.ssa Cassio, Dott. Baronio e Dott.ssa Ortolano (Pediatria), Dott.ssa Angeli (Cardiochirurgia), Dott. Arpinati (Ematologia)
  • Il gruppo collabora con le seguenti figure appartenenti ad altre istituzioni: Prof. M Maggi, Dott.ssa Fisher (UNIFI) e Prof.ssa Aloisi (UNISI)

Collaborazioni internazionali

  • National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development (USA)
  • World Health Organization (Svizzera)
  • Professor Stephanie Page (Endocrinology/Diabetes Clinic at Harborview, Univ. of Washington, USA)
  • Professor Christina Wang (Harbor UCLA Medical Center Endocrinology, USA)

Produzione scientifica

  1. Gava G, Mancini I, Orsili I, Bertelloni S, Alvisi S, Seracchioli R, Meriggiola MC. Bone mineral density, body composition and metabolic profiles in adult women with complete androgen insensitivity syndrome and removed gonads using oral or transdermal estrogens. Eur J Endocrinol. 2019 Sep 1.
  2. Gava G, Visconti M, Salvi F, Bartolomei I, Seracchioli R, Meriggiola MC. Prevalence and Psychopathological Determinants of Sexual Dysfunction and Related Distress in Women With and Without Multiple Sclerosis. J Sex Med. 2019 Jun;16(6):833-842.
  3. Gava G, Meriggiola MC. Update on male hormonal contraception. Ther Adv Endocrinol Metab. 2019 Mar
  4. Gava G, Alvisi S, Mancini I, Seracchioli R, Meriggiola MC. Prevalence of metabolic syndrome and its components in women with and without pelvic organ prolapse and its association with prolapse severity according to the Pelvic Organ Prolapse Quantification system. Int Urogynecol J. 2018 Dec 12.
  5. Gava G, Mancini I, Cerpolini S, Baldassarre M, Seracchioli R, Meriggiola MC. Testosterone undecanoate and testosterone enanthate injections are both effective and safe in transmen over 5 years of administration. Clin Endocrinol (Oxf). 2018 Jul 19.
  6. Mancini I, Rotilio A, Coati I, Seracchioli R, Martelli V, Meriggiola MC. Presentation of a meningioma in a transwoman after nine years of cyproterone acetate and estradiol intake: case report and literature review. Gynecol Endocrinol. 2018 Jun;34(6):456-459.
  7. Bertelloni S, Meriggiola MC, Dati E, Balsamo A, Baroncelli GI. Bone Mineral Density in Women Living with Complete Androgen Insensitivity Syndrome and Intact Testes or Removed Gonads. Sex Dev. 2017;11(4):182-189. doi: 10.1159/000477599.
  8. Alvisi S, Baldassarre M, Martelli V, Gava G, Seracchioli R, Meriggiola MC. Effects of ospemifene on vaginal epithelium of post-menopausal women. Gynecol Endocrinol. 2017 Dec;33(12):946-950.
  9. Behre HM, Zitzmann M, Anderson RA, Handelsman DJ, Lestari SW, McLachlan RI, Meriggiola MC, Misro MM, Noe G, Wu FC, Festin MP, Habib NA, Vogelsong KM, Callahan MM, Linton KA, Colvard DS. Efficacy and Safety of an Injectable Combination Hormonal Contraceptive for Men. J Clin Endocrinol Metab. 2016 Dec;101(12):4779-4788.
  10. Gava G, Cerpolini S, Martelli V, Battista G, Seracchioli R, Meriggiola MC. Cyproterone acetate vs leuprolide acetate in combination with transdermal oestradiol in transwomen: a comparison of safety and effectiveness. Clin Endocrinol (Oxf). 2016 Aug;85(2):239-46.
  11. Baldassarre M, Alvisi S, Mancini I, Moscatiello S, Marchesini G, Seracchioli R, Meriggiola MC. Impaired Lipid Profile is a Risk Factor for the Development of Sexual Dysfunction in Women. J Sex Med. 2016 Jan;13(1):46-54. 
  12. Baldassarre M, Alvisi S, Berra M, Martelli V, Farina A, Righi A, Meriggiola MC. Changes in vaginal physiology of menopausal women with type 2 diabetes. J Sex Med. 201;12(6):1346-55.
  13. Meriggiola MC, Gava G. Endocrine care of transpeople part II. A review of cross-sex hormonal treatments, outcomes and adverse effects in transwomen. Clin Endocrinol (Oxf). 2015 Nov;83(5):607-15.
  14. Meriggiola MC, Gava G. Endocrine care of transpeople part I. A review of cross-sex hormonal treatments, outcomes and adverse effects in transmen. Clin Endocrinol (Oxf). 2015 Nov;83(5):597-606.
  15. Pelusi C, Costantino A, Martelli V, Lambertini M, Bazzocchi A, Ponti F, Battista G, Venturoli S, Meriggiola MC. Effects of three different testosterone formulations in female-to-male transsexual persons. J Sex Med. 2014 Dec;11(12):3002-11.
  16. Fisher AD, Ristori J, Bandini E, Giordano S, Mosconi M, Jannini EA, Greggio NA, Godano A, Manieri C, Meriggiola C, Ricca V; Italian GnRH analogs study ONIG group, Dettore D, Maggi M. Medical treatment in gender dysphoric adolescents endorsed by SIAMS-SIE-SIEDP-ONIG.J Endocrinol Invest. 2014 Jul;37(7):675-87.
  17. Alvisi S, Baldassarre M, Lambertini M, Martelli V, Berra M, Moscatiello S, Marchesini G, Venturoli S, Meriggiola MC. Sexuality and psychopathological aspects in premenopausal women with metabolic syndrome. J Sex Med. 2014 Aug;11(8):2020-8.
  18. Gava G, Bartolomei I, Costantino A, Berra M, Venturoli S, Salvi F, Meriggiola MC. Long-term influence of combined oral contraceptive use on the clinical course of relapsing-remitting multiple sclerosis. Fertil Steril. 2014 Jul;102(1):116-22.
  19. Meriggiola MC, Berra M. Safety of hormonal treatment in transgenders. Curr Opin Endocrinol Diabetes Obes. 2013 Dec;20(6):565-9.
  20. Baldassarre M, Giannone FA, Foschini MP, Battaglia C, Busacchi P, Venturoli S, Meriggiola MC. Effects of long-term high dose testosterone administration on vaginal epithelium structure and estrogen receptor-αand -βexpression of young women. Int J Impot Res. 2013 Sep;25(5):172-7.